Continuous vs. intermittent hemodialysis: with which spin will my patient win?

Intervention: Patients were randomized to intermittent haemodialysis (n=184) or continuous venovenous haemodiafiltration (n=175). Guidelines were provided to achieve optimum haemodynamic tolerance and effectiveness of solute removal in both groups. The two groups were treated with the same polymer membrane and bicarbonate-based buffer. Measurements and main results: The primary endpoint was 60-day survival based on an intention-to-treat analysis. Rate of survival at 60-days did not differ between the groups (32% in the intermittent haemodialysis group versus 33% in the continuous renal replacement therapy group [95 % CI 8.8 to 11.1,]), or at any other time.